Idan za ku iya ba da gudummawar jini a gida maimakon a ofishin likita fa?Wannan shine jigo na Tasso, farawa na tushen Seattle wanda ke hawa cikin yanayin kula da lafiya.
Wanda ya kafa Tasso kuma Shugaba Ben Casavant ya shaida wa Forbes cewa kwanan nan kamfanin ya tara dala miliyan 100 karkashin jagorancin manajan saka hannun jari na kiwon lafiya RA Capital don haɓaka fasahar gwajin jini.Sabbin kudaden sun tayar da jimillar kudaden hannun jari zuwa dala miliyan 131.Casavant ya ƙi yin magana game da ƙimar, kodayake babban bayanan kasuwancin PitchBook ya kimanta shi akan dala miliyan 51 a cikin Yuli 2020.
"Wannan wuri ne mai ban mamaki wanda za a iya lalata shi da sauri," in ji Casavant."$ 100 miliyan yayi magana da kansa."
Kayan tattara jini na kamfanin-Tasso + (don jini mai ruwa), Tasso-M20 (don jinin da ba ya bushewa) da Tasso-SST (don shirya samfuran jinin ruwa marasa ƙarfi) - suna aiki a irin wannan hanya.Marasa lafiya kawai suna manne na'urar maɓalli mai girman ball ping-pong a hannunsu tare da manne mai nauyi kuma su danna babban maɓallin ja na na'urar, wanda ke haifar da vacuum.Lancet da ke cikin na'urar yana huda saman fata, kuma wani wuri yana jan jini daga capillaries zuwa cikin samfurin harsashi a kasan na'urar.
Na'urar tana tattara jinin capillary ne kawai, kwatankwacin bugun yatsa, ba jini mai jijiya ba, wanda kwararrun likitoci ne kawai ke iya karba.A cewar kamfanin, mahalarta a cikin nazarin asibiti sun ba da rahoton ƙananan zafi lokacin amfani da na'urar idan aka kwatanta da daidaitattun jini.Kamfanin yana fatan samun amincewar FDA a matsayin na'urar likitanci na Class II a shekara mai zuwa.
Anurag Kondapally, shugaban RA Capital, wanda zai shiga cikin kwamitin gudanarwa na Tasso ya ce "Za mu iya ziyartar likita kusan, amma idan kun shigo don yin gwaje-gwaje na asali, mayafin kama-karya ya karye."mafi kyawun shigar da tsarin kiwon lafiya da fatan inganta daidaito da sakamako."
Casawant, mai shekaru 34, yana da digirin digirgir na Ph.D.UW-Madison Biomedical engineering manyan ya kafa kamfanin a cikin 2012 tare da abokin aikin UW Erwin Berthier, 38, wanda shine CTO na kamfanin.A cikin dakin gwaje-gwaje na Jami'ar Washington a Madison farfesa David Beebe, sun yi nazarin microfluidics, wanda ke hulɗar da hali da kuma kula da ƙananan adadin ruwa a cikin hanyar sadarwa na tashoshi.
A cikin dakin gwaje-gwaje, sun fara tunanin duk sabbin fasahohin da dakin binciken zai iya yi wanda ke buƙatar samfuran jini da kuma wahalar samun su.Tafiya zuwa asibiti don ba da gudummawar jini ga likitan phlebotomist ko ma'aikacin jinya mai rijista yana da tsada kuma ba shi da daɗi, kuma huda yatsa yana da wahala kuma ba abin dogaro ba ne."Ka yi tunanin duniyar da maimakon yin tsalle a cikin mota da tuƙi a wani wuri, akwati ya bayyana a ƙofarka kuma za ka iya aika da sakamakon zuwa rikodin lafiyar lantarki," in ji shi."Mun ce, 'Zai yi kyau idan za mu iya sa na'urar ta yi aiki.'
"Sun fito da hanyar fasaha kuma tana da wayo sosai.Akwai wasu kamfanoni da yawa da ke ƙoƙarin yin hakan, amma ba su sami damar samar da mafita ta fasaha ba.”
Casavant da Berthier sun yi aiki maraice da karshen mako don haɓaka na'urar, da farko a cikin falon Casavan sannan kuma a cikin falon Berthier bayan abokin zama na Casavan ya nemi su zauna.A cikin 2017, sun gudanar da kamfanin ta hanyar Techstars mai mai da hankali kan kiwon lafiya kuma sun sami tallafin farko a cikin nau'in tallafin dala miliyan 2.9 daga Hukumar Ayyukan Binciken Ci Gaban Tsaro ta Tarayya (Darpa).Masu saka hannun jarinsa sun haɗa da Cedars-Sinai da Merck Global Innovation Fund, da kuma manyan kamfanoni Hambrecht Ducera, Foresite Capital da Vertical Venture Partners.Casavant ya yi imanin ya gwada samfurin sau ɗaruruwan yayin haɓakarsa."Ina son sanin samfurin sosai," in ji shi.
Lokacin da Jim Tananbaum, likita kuma wanda ya kafa manajan kadari na dala biliyan 4 Foresite Capital, ya yi tuntuɓe a kan Casavant kimanin shekaru uku da suka wuce, ya ce yana neman kamfani wanda zai iya yin phlebotomy a ko'ina."Wannan matsala ce mai matukar wahala," in ji shi.
Wahalar, in ji shi, ita ce, lokacin da kuka zana jini ta cikin capillary, matsa lamba yana fashe jajayen ƙwayoyin jinin, yana sa ba za a iya amfani da su ba."Sun fito da ingantaccen fasaha na fasaha," in ji shi."Akwai wasu kamfanoni da yawa da ke ƙoƙarin yin hakan amma ba su sami damar samar da hanyar fasaha ba."
Ga mutane da yawa, nan da nan kayayyakin da ake zana jini suna tuna wa Theranos, wanda ya yi alkawarin gwada jinin allura kafin hadarinsa a cikin 2018. An wulakanta mai shekaru 37 da haihuwa Elizabeth Holmes wanda ya kafa Elizabeth Holmes da laifin zamba kuma yana fuskantar daurin shekaru 20 a gidan yari. idan aka keta.
Kawai danna babban maɓallin ja: na'urar Tasso tana ba marasa lafiya damar ɗaukar jini a gida, ba tare da wani horo na likita ba.
"Abin farin ciki ne don bin labarin, kamar yadda muke," in ji Casavant."Tare da Tasso, koyaushe muna mai da hankali kan kimiyya.Duk game da sakamakon bincike ne, daidaito da daidaito.”
A halin yanzu ana amfani da samfuran tattarawar jini na Tasso a cikin gwaje-gwajen asibiti daban-daban a Pfizer, Eli Lilly, Merck da kuma aƙalla kamfanonin biopharmaceutical shida, in ji shi.A bara, Cibiyar Nazarin Ciwon daji ta Fred Hutchinson ta ƙaddamar da wani binciken Covid-19 don nazarin ƙimar kamuwa da cuta, lokacin watsawa, da yuwuwar sake kamuwa da cuta ta amfani da na'urar zana jini ta Tasso."Kungiyoyi da yawa da ke son gudanar da gwaji yayin bala'in suna buƙatar ingantacciyar hanya don isa ga marasa lafiya," in ji Casavant.
Tananbaum, wanda ke cikin jerin Forbes Midas a wannan shekara, ya yi imanin Tasso a ƙarshe zai iya yin girma zuwa ɗaruruwan miliyoyin raka'a a shekara yayin da farashin na'urar ya ragu kuma ana ƙara apps."Sun fara da shari'o'in tare da mafi girman buƙata da riba mafi girma," in ji shi.
Tasso yana shirin yin amfani da sabbin kudaden don fadada samarwa.A lokacin barkewar cutar, ta sayi wata shuka a Seattle wacce a baya ta ba da jiragen ruwa zuwa West Marine, wanda ya baiwa kamfanin damar rufe samarwa a ofisoshinsa.Wurin yana da matsakaicin ƙarfin na'urori 150,000 a kowane wata, ko miliyan 1.8 a kowace shekara.
Casavant ya ce "Idan aka ba da yawan adadin jini da gwajin jini a Amurka, za mu buƙaci ƙarin sarari," in ji Casavant.Ya yi kiyasin cewa akwai kimanin jini biliyan 1 a kowace shekara a Amurka, wanda dakunan gwaje-gwaje na yin gwaje-gwaje kimanin biliyan 10, yawancinsu suna taimakawa wajen magance cututtuka masu tsanani a cikin mutanen da suka tsufa."Muna duban sikelin da muke bukata da yadda za mu gina wannan kasuwancin," in ji shi.
RA Capital yana daya daga cikin manyan masu zuba jari na kiwon lafiya tare da dala biliyan 9.4 a karkashin gudanarwa har zuwa karshen Oktoba.
Lokacin aikawa: Maris 11-2023